Obiekwe B C, Sturdee D, Cockrill B L, Chard T
Br J Obstet Gynaecol. 1984 Nov;91(11):1077-80. doi: 10.1111/j.1471-0528.1984.tb15079.x.
Serum placental lactogen (hPL) was measured in serial blood samples obtained from 663 pregnant women at weekly intervals from 36 to 40 weeks. The group included 231 women with pre-eclampsia. Levels of hPL were significantly elevated in primigravidae with this condition but not in multigravidae. In all groups hPL levels were significantly reduced in association with growth retardation, but the clinical value of this observation appeared to be greater in multigravidae than in primigravidae. It is suggested that in primigravidae with pre-eclampsia maternal hPL levels reflect both the pathology of the disease as well as the condition of the fetus.
在36至40周期间，每周从663名孕妇身上采集系列血样，检测血清胎盘催乳素（hPL）。该组包括231名先兆子痫妇女。初产妇患此病时hPL水平显著升高，但经产妇则不然。在所有组中，hPL水平均随着胎儿生长受限而显著降低，但这一观察结果在经产妇中的临床价值似乎比初产妇更大。有人提出，初产妇患先兆子痫时，母体hPL水平既反映了疾病的病理情况，也反映了胎儿的状况。
