Saatov T S, Burkhanov S A, Usmanova G U
Biokhimiia. 1984 Aug;49(8):1291-4.
The ganglioside content in various organs of the rat were studied under normal conditions and under deficiency of thyroid hormones. The minimal ganglioside content was observed in skeletal muscles, the maximal one--in the brain. Using thin-layer chromatography, it was demonstrated that these organs possess a complex ganglioside composition which differs both qualitatively and quantitatively. Under thyroid hormone excess, the total ganglioside content shows a tendency to increase, while under hormone deficiency--to decrease. The nature of changes in individual ganglioside fractions in various tissues depends on the thyroid hormone content in the organism.
研究了正常条件下以及甲状腺激素缺乏时大鼠各器官中的神经节苷脂含量。在骨骼肌中观察到最低的神经节苷脂含量，在脑中观察到最高的含量。通过薄层色谱法表明，这些器官具有复杂的神经节苷脂组成，在质和量上都有所不同。甲状腺激素过量时，神经节苷脂总含量有增加的趋势，而激素缺乏时则有减少的趋势。不同组织中单个神经节苷脂组分的变化性质取决于机体中的甲状腺激素含量。
