Scheinman M M, Evans-Bell T
Circulation. 1984 Dec;70(6):1024-9. doi: 10.1161/01.cir.70.6.1024.
An international registry was formed to collate data for patients undergoing attempted catheter ablation of the atrioventricular (AV) junction and insertion of a permanent pacemaker. Over the past 2 years, data was submitted for 127 patients who were followed for a mean of 9.9 +/- 8.2 months. The most common arrhythmia treated was chronic or paroxysmal atrial fibrillation or flutter (78 patients, 61%); the remainder had supraventricular tachycardia due to AV node reentry, ectopic atrial tachycardia, or incorporated an accessory pathway. A single shock of 150 to 400 J was effective in producing chronic third-degree AV block in 45 patients while two or more shocks were used in an additional 45 patients. There was no significant difference in the total cumulative energy used in successful and unsuccessful procedures. Immediate complications related to the shock included ventricular fibrillation (one patient), pericardial tamponade (one patient), and transient hypotension (one patient). No chronic sequelae occurred as a result of these complications. Late complications (1 day to 1 month) included ventricular tachycardia (three patients), sepsis involving the pacemaker pocket (two patients), staphylococcal sepsis from temporary pacing catheter (one patient), thrombophlebitis (one patient), thrombosis of the left subclavian vein (one patient), and hemothorax (one patient). Follow-up evaluation revealed chronic third degree AV block in 90 (71%) and AV conduction resumed but no drugs were required for arrhythmia control in eight (6.5%) and arrhythmia control was achieved with previously ineffective drugs in 16 (13%). Thirteen patients (10%) had no improvement and five of these patients underwent cardiac electrosurgery for direct His bundle ablation.(ABSTRACT TRUNCATED AT 250 WORDS)
一个国际注册机构成立,旨在收集接受房室(AV)结导管消融术及植入永久起搏器患者的数据。在过去2年中,提交了127例患者的数据,这些患者平均随访9.9±8.2个月。治疗的最常见心律失常为慢性或阵发性心房颤动或扑动(78例患者,61%);其余患者因房室结折返、异位房性心动过速或合并旁路而患有室上性心动过速。单次150至400焦耳的电击对45例患者有效产生慢性三度房室传导阻滞,另外45例患者使用了两次或更多次电击。成功和失败手术中使用的总累积能量无显著差异。与电击相关的即刻并发症包括心室颤动(1例患者)、心包填塞(1例患者)和短暂性低血压(1例患者)。这些并发症未导致慢性后遗症。晚期并发症(1天至1个月)包括室性心动过速(3例患者)、起搏器囊袋感染(2例患者)、临时起搏导管引起的葡萄球菌败血症(1例患者)、血栓性静脉炎(1例患者)、左锁骨下静脉血栓形成(1例患者)和血胸(1例患者)。随访评估显示90例(71%)为慢性三度房室传导阻滞,8例(6.5%)房室传导恢复但心律失常控制无需用药,16例(13%)使用先前无效的药物实现了心律失常控制。13例患者(10%)无改善,其中5例患者接受了心脏电外科手术以直接消融希氏束。(摘要截断于250字)