Comparative predictive value of ST-segment depression or angina during early and repeat postinfarction exercise tests.

To determine the relative value of electrocardiographic (ECG) ST-segment depression alone compared to angina alone for predicting multivessel coronary artery disease during early and repeat postinfarction exercise tests, we evaluated 93 postmyocardial infarction patients with modified treadmill exercise tests prior to hospital discharge (mean 14 +/- 2 days), and 36 of these 93 patients with repeat exercise tests at six weeks following infarction. It was concluded that angina alone or angina irrespective of the presence of ST-segment depression are better predictors of multivessel coronary artery disease than ECG ST-segment depression alone, and the persistence of ischemic abnormalities during repeat treadmill exercise tests following infarction is useful for confirming the presence of multivessel coronary artery disease.