Jederlinic P, Muspratt J A, Miller M J
Chest. 1984 Dec;86(6):870-3. doi: 10.1378/chest.86.6.870.
Six healthy volunteers and 19 patients with stable chronic obstructive pulmonary disease underwent a multistage, maximal, ventilatory stress test, ie, serial imposition of increasingly severe resistances to inspiration by means of a commercially available device (Pflex Inspiratory Trainer). Patients consistently underventilated and suffered desaturation during the test; healthy individuals did not. Eight patients completed three weeks or more of daily training stints using the inspiratory resistive device. There was no significant improvement in performance of the test after training. Those individuals whose condition improved showed no discernible change in ventilatory pattern but did suffer further desaturation.
6名健康志愿者和19名稳定期慢性阻塞性肺疾病患者接受了一项多阶段、最大通气应激测试，即通过一种商用设备（Pflex吸气训练器）连续施加逐渐增加的吸气阻力。患者在测试过程中始终通气不足并出现血氧饱和度下降；健康个体则没有。8名患者使用吸气阻力设备完成了为期三周或更长时间的每日训练。训练后测试表现没有显著改善。病情有所改善的个体通气模式没有明显变化，但血氧饱和度进一步下降。
