Sonne L J, Davis J A
Chest. 1982 Apr;81(4):436-9. doi: 10.1378/chest.81.4.436.
Six patients with severe chronic obstructive pulmonary disease underwent a six-week outpatient program to train their respiratory muscles with an inspiratory resistive device. Exercise performance was measured using a cycle ergometer. Maximum exercise capacity, represented by VO2 max, increased 15 percent. The maximum work rate increased 37 percent, and the minute ventilation attained during exercise increased 17 percent after training. Respiratory muscle endurance increased 56 percent. All patients reported an increased ability to perform the activities of daily living. No changes were reported in three patients who underwent sham training.
六名重度慢性阻塞性肺疾病患者参加了一个为期六周的门诊项目，使用吸气阻力装置训练呼吸肌。使用自行车测力计测量运动表现。以最大摄氧量（VO2 max）表示的最大运动能力提高了15%。最大工作率提高了37%，训练后运动期间达到的每分通气量增加了17%。呼吸肌耐力提高了56%。所有患者均报告日常生活活动能力有所提高。接受假训练的三名患者未报告有变化。
