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[人淋巴样Raji细胞系培养物在全氟碳乳剂及其单独成分毒性试验中的应用]

[Use of the human lymphoid Raji-line cell culture in tests of the toxicity of perfluorocarbon emulsions and their separate components].

作者信息

Arkhipov V V, Narimanov A A

出版信息

Farmakol Toksikol. 1984 Sep-Oct;47(5):117-20.

PMID:6500028
Abstract

The possibility has been shown of utilizing the culture of human lymphoid Raji cells as a highly sensitive object for toxicity testing of perfluorocarbon emulsions and their components. It has been disclosed that cytotoxicity of perfluorocarbon emulsions is primarily determined by its stabilizers--proxanoles. Theoretically, the cultures of animal cells are considered to be useful for toxicological studies.

摘要

已经证明利用人淋巴样Raji细胞培养物作为全氟碳乳液及其成分毒性测试的高敏感对象是可能的。据披露,全氟碳乳液的细胞毒性主要由其稳定剂——泊洛沙姆决定。从理论上讲,动物细胞培养物被认为对毒理学研究有用。

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