Haney A F, Handwerger S, Weinberg J B
Fertil Steril. 1984 Dec;42(6):935-8.
To evaluate the functional status of endometriotic implants, a luteal secretory product of endometrium, PRL, was measured in the PF of 27 infertile women with endometriosis, 13 infertile women without endometriosis, and 11 fertile women undergoing elective sterilization. PF PRL concentrations and PF/plasma PRL ratios were similar in all the groups and did not vary with the menstrual cycle or the stage of endometriosis. These data demonstrate that the ectopic endometrium in infertile women with endometriosis does not secrete PRL in amounts sufficient to elevate PF concentrations and suggest that the infertility observed in these women is probably not dependent upon the secretory activity of endometriotic implants.
为评估子宫内膜异位症植入物的功能状态，检测了27例患有子宫内膜异位症的不孕女性、13例无子宫内膜异位症的不孕女性以及11例接受选择性绝育的有生育能力女性的腹腔液中一种子宫内膜黄体期分泌产物——催乳素（PRL）的水平。所有组的腹腔液PRL浓度及腹腔液/血浆PRL比值相似，且不随月经周期或子宫内膜异位症的分期而变化。这些数据表明，患有子宫内膜异位症的不孕女性的异位子宫内膜分泌的PRL量不足以提高腹腔液浓度，并提示这些女性中观察到的不孕可能不依赖于子宫内膜异位症植入物的分泌活性。
