Matthys H, Zaiss A, Ende K
Fortschr Med. 1984 Oct 18;102(39):996-9.
After an initial inhalation of 1,25 mg fenoterol in 2 ml 0,9% NaCl by means of Pari Privat randomized on the following two days, two groups of ten respectively eleven patients with relatively stable respiratory tract obstruction were tested for the reversibility of the obstruction with a metered dose inhaler as follows: Group 1 (10 patients) received the metered dose inhaler with a small expander alternatively on even days and on the odd days without the expander. Group 2 (11 patients) received the metered dose inhaler with the large expander (130 mm X 35 mm) alternatively on the even days and with the small expander (100 mm X 30 mm) on the odd days. All patients showed a significant improvement of the bronchial obstruction regardless of the type of inhalation. Auxiliary appliances (inhalation appliances, expanders for the metered dose inhaler) are therefore only necessary, when the patients cannot cope at all or cannot cope optimally with the simple metered dose aerosol.
通过Pari Privat雾化器，首先让患者吸入2毫升0.9%氯化钠溶液中含有的1.25毫克非诺特罗，随后在接下来的两天里，对两组分别为10名和11名呼吸道梗阻相对稳定的患者进行如下测试，以评估使用定量吸入器时梗阻的可逆性：第一组（10名患者）在偶数日使用带有小型扩张器的定量吸入器，在奇数日不使用扩张器。第二组（11名患者）在偶数日使用大型扩张器（130毫米×35毫米）的定量吸入器，在奇数日使用小型扩张器（100毫米×30毫米）。无论吸入类型如何，所有患者的支气管梗阻均有显著改善。因此，只有当患者根本无法或无法最佳地使用简单的定量气雾剂时，才需要辅助器具（吸入器具、定量吸入器的扩张器）。
