Ferrante A, Rencis V O
Immunol Lett. 1984;8(4):215-7. doi: 10.1016/0165-2478(84)90081-6.
The effect of human fibroblast interferon (HuIFN-beta) on the HMP shunt activity of human polymorphonuclear leucocytes (PMNLs) was examined. HuIFN-beta caused an increase in the base level of the HMP shunt activity. No significant increase was observed in the same PMNLs stimulated with opsonized zymosan. The augmentation of this property, generally associated with antimicrobial and cytotoxic properties of the PMNLs, may be of potential importance in host defences against microbial and malignant diseases.
研究了人成纤维细胞干扰素（HuIFN-β）对人多形核白细胞（PMNLs）磷酸戊糖途径（HMP）活性的影响。HuIFN-β导致HMP途径活性的基础水平升高。在用调理酵母聚糖刺激的相同PMNLs中未观察到显著增加。这种特性的增强通常与PMNLs的抗菌和细胞毒性特性相关，可能在宿主抵御微生物和恶性疾病中具有潜在重要性。
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