Howard M L, Baldwin J N, Kobayashi R H, Jensen B K
J Asthma. 1984;21(5):299-303. doi: 10.3109/02770908409077440.
This study indicates that a sustained-release tablet may be used in certain young children on an every-12-hr dosing schedule with acceptable serum theophylline fluctuation. Many young children are able to swallow the tablet and dosing increments are convenient.
本研究表明，缓释片可用于某些幼儿，采用每12小时一次的给药方案，血清茶碱波动可接受。许多幼儿能够吞咽该片剂，且剂量增加方便。
