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[肠道碳水化合物吸收——形态学与生物化学之间的相关性(作者译)]

[Intestinal carbohydrate absorption--correlation between morphology and biochemistry (author's transl)].

作者信息

Böhmer R

出版信息

J Clin Chem Clin Biochem. 1978 Mar;16(3):153-63.

PMID:650157
Abstract

After a short description of the morphology of the small intestinal mucosa the physiological processes of carbohydrate digestion and absorption are discussed. While starch is hydrolyzed by amylase in the lumen of the duodenum, the disaccharide hydrolysis does not take place in the intestinal lumen, but at the brush border membrane of the enterocyte. The liberated monosaccharides are--at least in part--absorbed by a specific active transport system. This mechanism is different from those which are responsible for the active transport of primary monosaccharides, i.e. monosaccharides which do not result from oligosaccharide hydrolysis. The exit process for monosaccharides out of the enterocyte into the extracellular space occurs by "facilitated diffusion". Passage through "fenestrated" capillaries is discussed as a possible mechanism for the entry of monosaccharides into the blood vessel system.

摘要

在简短描述小肠黏膜的形态学之后,讨论了碳水化合物消化和吸收的生理过程。淀粉在十二指肠腔内被淀粉酶水解,而双糖水解并非发生在肠腔内,而是在肠上皮细胞的刷状缘膜处。释放出的单糖至少部分通过特定的主动转运系统被吸收。该机制不同于负责原发性单糖(即并非由寡糖水解产生的单糖)主动转运的机制。单糖从肠上皮细胞进入细胞外空间的排出过程是通过“易化扩散”进行的。穿过“有窗孔的”毛细血管被认为是单糖进入血管系统的一种可能机制。

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