Kroll P, Port F K, Silk K R
J Nerv Ment Dis. 1978 Apr;166(4):291-3. doi: 10.1097/00005053-197804000-00008.
A preliminary, uncontrolled study utilizing hemodialysis in the treatment of chronic schizophrenia reported a high success rate. Two patients are presented who had both schizophrenia and chronic renal failure and who underwent intensive, long term hemodialysis with no change in their schizophrenic symptomatology. This negative finding is consistent with other case reports. Retrospective or limited controlled studies based on previous research with false neurotransmitters, serum protein factors, or endorphins in schizophrenia are urged before further patients with normal kidney function are exposed to the risks of hemodialysis.
一项利用血液透析治疗慢性精神分裂症的初步非对照研究报告了较高的成功率。本文介绍了两名同时患有精神分裂症和慢性肾衰竭的患者，他们接受了强化、长期的血液透析，但精神分裂症症状并无改变。这一阴性结果与其他病例报告一致。在有更多肾功能正常的患者面临血液透析风险之前，迫切需要基于之前对精神分裂症中假神经递质、血清蛋白因子或内啡肽的研究进行回顾性或有限对照研究。
