Scheiber S C, Cohen I, Yamamura H, Noval R, Beutler L
Am J Psychiatry. 1981 May;138(5):662-5. doi: 10.1176/ajp.138.5.662.
The authors evaluated hemodialysis as a treatment for schizophrenia in an uncontrolled study of 11 patients. Eight men and two women with chronic schizophrenia who had responded poorly to conventional treatments or who had sought alternate treatments received three dialyses weekly for 3 weeks; 1 additional subject dropped out after eight treatments. MMPI, Psychiatric Status Scale, and Inpatient Multidimensional Psychiatric Scale scores were obtained before, immediately following, and at intervals after the nine treatments. Preliminary results, including 1-month follow-up, suggest that subjects with pretreatment anxiety and depression improved. No endorphins were discovered in the dialysate.
作者在一项针对11名患者的非对照研究中评估了血液透析作为精神分裂症的一种治疗方法。8名男性和2名女性慢性精神分裂症患者，对传统治疗反应不佳或寻求替代治疗，每周接受3次透析，共3周；另有1名受试者在8次治疗后退出。在9次治疗前、治疗后立即以及治疗后的不同时间间隔，获取明尼苏达多相人格调查表（MMPI）、精神状态量表和住院多维精神病量表的评分。初步结果，包括1个月的随访，表明治疗前有焦虑和抑郁症状的受试者有所改善。透析液中未发现内啡肽。
