Mackel R, Brink E E, Nakajima Y
J Neurol Neurosurg Psychiatry. 1984 Oct;47(10):1109-16. doi: 10.1136/jnnp.47.10.1109.
The effects of tizanidine on the electromyographic responses of forearm flexors and extensors to torque disturbances were studied in normal subjects. Tizanidine had a strong depressive action on all the reflex responses, and on muscle background activity. It is concluded that the action on reflexes is not specific, but secondary to decreased spinal cord excitability.
在正常受试者中研究了替扎尼定对前臂屈肌和伸肌肌电反应以应对扭矩干扰的影响。替扎尼定对所有反射反应及肌肉背景活动均有强烈的抑制作用。得出的结论是，其对反射的作用并非特异性的，而是继发于脊髓兴奋性降低。
