Hermann G A, Tholen D W, Herrera N E
J Nucl Med. 1984 Dec;25(12):1371-4.
Using simulators of transmission imaging, an interlaboratory survey assessed the discriminatory performance of 86 subscribers, each of whom imaged a liver phantom in anterior and right lateral projections. Analysis was by receiver operating characteristic (ROC) with Az, the area under the ROC curve, used as a measure of accuracy unconfounded by decision bias. Az values were then defined as the dependent variable in a statistical model that related performance to several instrument design and operating parameters. Six of 14 postulated parameters explained approximately half of observed subscriber variability. These were: year of camera manufacture or upgrade, number of photomultiplier tubes, collimator type, total counts collected, use of a Co-57 disk source for imaging the phantom, and computer processing of the image. The findings confirm previous inferences drawn from controlled intralaboratory experimentation, but hitherto unsubstantiated by clinical imaging data.
通过使用透射成像模拟器，一项实验室间调查评估了86位参与者的鉴别性能，每位参与者都从前位和右侧位对肝脏模型进行成像。分析采用了受试者工作特征曲线（ROC），以ROC曲线下面积（Az）作为衡量准确性的指标，该指标不受决策偏差的影响。然后，将Az值定义为一个统计模型中的因变量，该模型将性能与多个仪器设计和操作参数相关联。14个假定参数中的6个参数解释了约一半观察到的参与者变异性。这些参数分别是：相机制造或升级年份、光电倍增管数量、准直器类型、采集的总计数、使用Co-57圆盘源对模型进行成像以及图像的计算机处理。这些发现证实了先前从实验室内部对照实验得出的推论，但迄今为止尚未得到临床成像数据的证实。
