人体脑脊液流体动力学研究。2. 与脑脊液压力和流量相关的正常流体动力学变量。
CSF hydrodynamic studies in man. 2 . Normal hydrodynamic variables related to CSF pressure and flow.
作者信息
Ekstedt J
出版信息
J Neurol Neurosurg Psychiatry. 1978 Apr;41(4):345-53. doi: 10.1136/jnnp.41.4.345.
Abstract
With the patient in the supine position, the subarachnoidal space was infused with artificial CSF at several constant pressure levels. The resulting flow of liquid was recorded. By draining CSF at a low pressure the CSF production rate was determined. Normal values are given and discussed for (1) the resting pressure, (2) the conductance of the CSF outflow pathways, (3) the formation rate of CSF, (4) the pressure difference across the CSF outflow pathways, and (5) the sagittal sinus pressure. None of the variables showed any age dependence, nor was there any sex difference.
摘要
患者处于仰卧位时，在几个恒定压力水平下向蛛网膜下腔注入人工脑脊液。记录由此产生的液体流量。通过在低压下引流脑脊液来测定脑脊液生成率。给出并讨论了以下各项的正常值：(1)静息压力，(2)脑脊液流出途径的传导性，(3)脑脊液生成率，(4)脑脊液流出途径两端的压力差，以及(5)矢状窦压力。这些变量均未显示出任何年龄依赖性，也不存在性别差异。
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CSF hydrodynamic studies in man. 2 . Normal hydrodynamic variables related to CSF pressure and flow.人体脑脊液流体动力学研究。2. 与脑脊液压力和流量相关的正常流体动力学变量。
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本文引用的文献
1
HYDROCEPHALUS: CHANGES IN FORMATION AND ABSORPTION OF CEREBROSPINAL FLUID WITHIN THE CEREBRAL VENTRICLES.脑积水：脑室内脑脊液形成与吸收的变化
J Neurosurg. 1963 Dec;20:1050-63. doi: 10.3171/jns.1963.20.12.1050.
2
DURAL SINUS PRESSURE. IN NORMAL AND HYDROCEPHALIC DOGS.
Arch Neurol. 1964 Jun;10:575-80. doi: 10.1001/archneur.1964.00460180041003.
3
Bulk flow and diffusion in the cerebrospinal fluid system of the goat.山羊脑脊液系统中的 bulk flow 和扩散。
注：“bulk flow”直译为“体积流”，在医学领域可能有更专业的特定表述，需结合具体语境进一步理解其准确含义。
Am J Physiol. 1962 Nov;203:775-81. doi: 10.1152/ajplegacy.1962.203.5.775.
4
The cerebrospinal fluid valves.脑脊液瓣膜
Brain. 1960 Sep;83:454-69. doi: 10.1093/brain/83.3.454.
5
Exchange of albumin between blood, cerebrospinal fluid, and brain in the cat.猫的血液、脑脊液和脑之间白蛋白的交换
Am J Physiol. 1967 May;212(5):1199-204. doi: 10.1152/ajplegacy.1967.212.5.1199.
6
The production of cerebrospinal fluid in man and its modification by acetazolamide.人体脑脊液的生成及其受乙酰唑胺的影响。
J Neurosurg. 1966 Oct;25(4):430-6. doi: 10.3171/jns.1966.25.4.0430.
7
Normal cerebrospinal-fluid pressure.正常脑脊液压力。
N Engl J Med. 1969 Apr 17;280(16):904-5.
8
Cerebrospinal fluid formation and bulk absorption in the freshwater turtle.淡水龟脑脊液的形成与大量吸收
Exp Neurol. 1971 May;31(2):258-62. doi: 10.1016/0014-4886(71)90194-4.
9
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Brain. 1970;93(4):665-78. doi: 10.1093/brain/93.4.665.
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A simple constant-infusion manometric test for measurement of CSF absorption. I. Rationale and method.一种用于测量脑脊液吸收的简单恒速输注测压试验。I. 原理与方法。
Neurology. 1970 Jun;20(6):534-44. doi: 10.1212/wnl.20.6.534.
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