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高丙氧芬浓度。

A high propoxyphene concentration.

作者信息

Eberhardt R D, Cash D K, Oehldrich J R

出版信息

J Anal Toxicol. 1984 Sep-Oct;8(5):246-7. doi: 10.1093/jat/8.5.246.

DOI:10.1093/jat/8.5.246
PMID:6503231
Abstract

Approximately 10% of reported fatal poisonings with propoxyphene have blood concentrations exceeding 10 mg/L. A few have concentrations exceeding 100 mg/L. It is evident, therefore, that the blood does not reach propoxyphene "saturation" at either concentration. The ratios of propoxyphene to norpropoxyphene do not appear to differ markedly between drug abuse deaths and nonabuse deaths.

摘要

据报告,丙氧芬致死中毒案例中约10%的血液浓度超过10毫克/升。少数案例的浓度超过100毫克/升。因此,很明显,在这两种浓度下血液都未达到丙氧芬的“饱和”状态。在药物滥用致死案例和非滥用致死案例中,丙氧芬与去甲丙氧芬的比例似乎没有显著差异。

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引用本文的文献

1
[Sustained-release dextropropoxyphene.].[缓释右丙氧芬。]
Schmerz. 1991 Dec;5(4):233-42. doi: 10.1007/BF02527803.
2
Fatal dextropropoxyphene poisonings in Jutland, Denmark.
Z Rechtsmed. 1989;102(2-3):107-15. doi: 10.1007/BF00200504.