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接受治疗的酗酒者和吸毒成瘾者的死亡率:戒酒的益处。

Mortality of treated alcoholics and drug addicts: the benefits of abstinence.

作者信息

Barr H L, Antes D, Ottenberg D J, Rosen A

出版信息

J Stud Alcohol. 1984 Sep;45(5):440-52. doi: 10.15288/jsa.1984.45.440.

Abstract

A study of 2-yr treatment outcome and of mortality in the following 8 yr was conducted on all first admissions to Eagleville Hospital in 1970 (503 alcoholics and 221 drug addicts; 9% women). The average age of the alcoholics was 41.6 vs 23.0 for the drug addicts. Status (misusing vs not misusing) 2 yr after admission for treatment or at death was ascertained for 92% of the subjects. The 108 known deaths occurred in 18.5% of the alcoholics and 6.8% of the addicts. Death rates per 1000 person yr at risk were compared with expected general population rates, controlling for age, race and sex. Overall, mortality per 1000 person yr was 25.9 for alcoholics and 8.8 for addicts, each higher than expectancy (p less than .001). Ratios of observed to expected rates were similar (2.5 and 3.1, respectively). Excess mortality occurred only among those misusing alcohol or drugs at 2 yr; nonmisusers had expected death rates. Disease and violent deaths were excessive among alcoholics, but only violent deaths exceeded expectancy among drug addicts. Of the 108 deaths, 66 were excess deaths, attributable to substance misuse and the associated way of life. However, among the 254 who were not misusing on follow-up, 19 died rather than the 51 who would have died if their mortality had been that of the persistent misusers.

摘要

对1970年首次入住伊格维尔医院的所有患者(503名酗酒者和221名吸毒成瘾者;9%为女性)进行了一项研究,观察其2年治疗结果以及随后8年的死亡率。酗酒者的平均年龄为41.6岁,而吸毒成瘾者为23.0岁。92%的受试者在入院接受治疗2年后或死亡时的状态(滥用与否)得以确定。108例已知死亡病例中,酗酒者占18.5%,吸毒成瘾者占6.8%。将每1000人年的死亡率与预期的一般人群死亡率进行比较,并对年龄、种族和性别进行了控制。总体而言,酗酒者每1000人年的死亡率为25.9,吸毒成瘾者为8.8,均高于预期(p<0.001)。观察到的与预期的死亡率之比相似(分别为2.5和3.1)。仅在2年时滥用酒精或药物的人群中出现了超额死亡率;未滥用者的死亡率与预期相符。酗酒者中因疾病和暴力导致的死亡人数过多,但吸毒成瘾者中只有暴力死亡人数超过预期。在108例死亡病例中,66例为超额死亡,归因于物质滥用及相关的生活方式。然而,在随访中未滥用物质的254人中,有19人死亡,而如果他们的死亡率与持续滥用者相同,本应有51人死亡。

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