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[生物体和环境中特殊金属的转化反应。3. 大鼠体内氯化汞(II)与三氯化一甲基锡之间的反应]

[Transformation reactions of special metals in organisms and in the environment. 3. In vivo reactions between mercury II chloride and monomethyltin trichloride in rats].

作者信息

Woggon H, Klein S, Plass R, Nickel B

出版信息

Nahrung. 1984;28(9):995-1002. doi: 10.1002/food.19840280912.

DOI:10.1002/food.19840280912
PMID:6504121
Abstract

Following the comments on the metabolism and the toxicity of methylmercury compounds as well as on the interaction with food components and a few environmental chemicals from literature study, the results of the in vivo experiments for examining the reaction between HgCl2 and CH3SnCl3 in the gastrointestinal tract and the subsequent distribution of the formed methylmercury are reported. The reaction between both of the substances proceeding in aqueous solution with immediate formation of methylmercury also leads in the intestinal tract very rapidly to the formation of methylmercury and its distribution into various organs. An increase in the relative weight of liver and kidneys was evident.

摘要

根据文献研究中关于甲基汞化合物的代谢、毒性以及与食物成分和一些环境化学物质相互作用的评论,报告了用于研究胃肠道中HgCl2与CH3SnCl3之间反应以及所形成甲基汞随后分布情况的体内实验结果。两种物质在水溶液中发生反应并立即形成甲基汞,这在肠道中也会很快导致甲基汞的形成及其在各个器官中的分布。肝脏和肾脏的相对重量明显增加。

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