Wyllie E, Lüders H, MacMillan J P, Gupta M
Neurology. 1984 Dec;34(12):1601-4. doi: 10.1212/wnl.34.12.1601.
We prospectively studied serum prolactin (PRL) elevation after different types of documented seizures in 17 patients. Marked PRL elevations above normal and above three times baseline were seen at 15 or 30 minutes after 20 of 25 (80%) generalized tonic-clonic, 13 of 30 (43%) complex partial, and 1 of 10 (10%) simple partial seizures. Although marked postictal PRL elevation is a sensitive indicator of recent epileptic seizures, a normal 15- or 30-minute postictal PRL level does not exclude an epileptic seizure.
我们前瞻性地研究了17例患者在不同类型的确诊癫痫发作后的血清催乳素（PRL）升高情况。在25次全身性强直阵挛发作中的20次（80%）、30次复杂部分性发作中的13次（43%）以及10次简单部分性发作中的1次（10%）发作后的15或30分钟时，观察到催乳素显著升高至高于正常水平且高于基线水平的三倍。虽然发作后催乳素显著升高是近期癫痫发作的敏感指标，但发作后15或30分钟时催乳素水平正常并不能排除癫痫发作。
