各种癫痫发作后的血清催乳素、皮质醇和生长激素浓度。

Serum prolactin, cortisol and growth hormone concentrations after various epileptic seizures.

作者信息

Takeshita H, Kawahara R, Nagabuchi T, Mizukawa R, Hazama H

出版信息

Jpn J Psychiatry Neurol. 1986 Dec;40(4):617-23. doi: 10.1111/j.1440-1819.1986.tb03176.x.

DOI:10.1111/j.1440-1819.1986.tb03176.x

Abstract

The serial serum concentrations of prolactin (PRL), cortisol and growth hormone (GH) were measured after clinical fits of seizures in 49 epileptic patients, aged 13-77. In generalized tonic-clonic seizures, both the serum PRL and cortisol levels transiently rose and reached their maximum 30 min after the onset of clinical fits. Serum GHs were elevated in some of the patients. After complex partial seizures, significant rises were found only in serum cortisol, but no demonstrable change was observed in PRL and GH. In the other minor seizure group, no remarkable change was observed in any of the hormones. These results suggest that the postictal hormonal change is different in each type of seizure, respectively.

摘要

对49名年龄在13至77岁之间的癫痫患者，在癫痫发作临床发作后测量了催乳素（PRL）、皮质醇和生长激素（GH）的系列血清浓度。在全身强直阵挛性发作中，血清PRL和皮质醇水平均短暂升高，并在临床发作开始后30分钟达到峰值。部分患者血清GH升高。复杂部分性发作后，仅血清皮质醇显著升高，但PRL和GH未观察到明显变化。在其他轻度发作组中，任何激素均未观察到显著变化。这些结果表明，每种癫痫发作类型的发作后激素变化各不相同。