Tewe O O
Toxicol Lett. 1984 Nov;23(2):169-76. doi: 10.1016/0378-4274(84)90122-x.
Thiocyanate concentrations of serum, liver, kidney, spleen and longissimus dorsi were determined in 64 growing Large White x Landrace pigs offered 8 experimental isocaloric diets containing different levels of cassava peel and crude protein. Cassava peel increased serum thiocyanate on day 60 (P less than 0.01) and day 90 (P less than 0.01) of the trial, while the crude protein level increased it (P less than 0.05) on days 30 and 90, respectively. Interaction of the two factors was significant on day 30 (P less than 0.05) and day 90 (P less than 0.05). There was a correlation between cyanide intake and serum thiocyanate level. Coefficient of determination revealed that cyanide alone accounted for 28.5; 60.6 and 48.8% variation in serum thiocyanate on days 30, 60 and 90, respectively. Liver, spleen and longissimus dorsi thiocyanate were affected by dietary protein intake (P less than 0.05). Thiocyanate concentration was higher (P less than 0.05) on cassava peel diet. Generally, crude protein at 5% reduced organ and muscle thiocyanate concentrations. A diet containing 112.2-117.3 mg/kg hydrocyanic acid (HCN) affected serum but not organ and muscle thiocyanate in protein-sufficient diets.
对64头生长中的大白猪×长白猪杂交猪进行试验,给它们投喂8种等热量的试验日粮,这些日粮含有不同水平的木薯皮和粗蛋白,测定了它们血清、肝脏、肾脏、脾脏和背最长肌中的硫氰酸盐浓度。在试验的第60天(P<0.01)和第90天(P<0.01),木薯皮使血清硫氰酸盐增加,而粗蛋白水平分别在第30天和第90天使其增加(P<0.05)。这两个因素的交互作用在第30天(P<0.05)和第90天(P<0.05)具有显著意义。氰化物摄入量与血清硫氰酸盐水平之间存在相关性。决定系数显示,仅氰化物分别占第30天、第60天和第90天血清硫氰酸盐变化的28.5%、60.6%和48.8%。肝脏、脾脏和背最长肌中的硫氰酸盐受日粮蛋白质摄入量的影响(P<0.05)。木薯皮日粮的硫氰酸盐浓度更高(P<0.05)。一般来说,5%的粗蛋白降低了器官和肌肉中的硫氰酸盐浓度。在蛋白质充足的日粮中,含有112.2 - 117.3毫克/千克氢氰酸(HCN)的日粮影响血清中的硫氰酸盐,但不影响器官和肌肉中的硫氰酸盐。