Vakov L, Orbetsova V
Vutr Boles. 1984;23(4):72-9.
The 24-h excretion of free, conjugated and total fractions of dopa, dopamine, noradrenaline and adrenaline was studied in 32 patients with diabetes mellitus. Adrenaline and dopamine were established to be increased--dopa decreased and noradrenaline--not changed. An attempt is made to explain the hormonal changes on the base of the analysis of the so called synthetic and dissociative coefficients of catecholamines. A moderate reverse correlation of the changes with the age of the patients and duration of diabetes was established as well as lower values in the female-diabetics versus the male-diabetics. The hormonal deviations are associated with the disturbances in the carbohydrate metabolism, have a reactive character and are manifested in insulin-dependent type of diabetes.
对32例糖尿病患者的多巴、多巴胺、去甲肾上腺素和肾上腺素的游离、结合及总成分的24小时排泄情况进行了研究。结果发现肾上腺素和多巴胺排泄增加，多巴排泄减少，而去甲肾上腺素排泄未发生变化。通过对儿茶酚胺所谓的合成和分解系数进行分析，试图解释这些激素变化。研究还发现这些变化与患者年龄和糖尿病病程呈中度负相关，且女性糖尿病患者的数值低于男性糖尿病患者。激素偏差与碳水化合物代谢紊乱有关，具有反应性特征，并在胰岛素依赖型糖尿病中表现出来。
