Vakov L
Vutr Boles. 1985;24(1):108-12.
The 24-h urine excretion of free, conjugated and total fraction of Dopa, dopamine, noradrenaline and adrenaline was studied in diabetics with normal weight and overweight. A tendency to lower excretion of adrenaline, noradrenaline and dopamine was established in diabetics with overweight as well as a tendency to reverse correlation between overweight and urine excretion of catecholamines. On the base of the so called synthesis and degradation coefficients, the possibility the changes established in the diabetics with overweight to be due to reduced synthesis of dopamine and noradrenaline is discussed. A presumption is presented about the possible causative relation between the reduction of catecholamine excretion and overweight in diabetics.
对体重正常和超重的糖尿病患者的游离、结合及总多巴、多巴胺、去甲肾上腺素和肾上腺素的24小时尿排泄情况进行了研究。超重糖尿病患者中存在肾上腺素、去甲肾上腺素和多巴胺排泄降低的趋势,以及超重与儿茶酚胺尿排泄之间的负相关趋势。基于所谓的合成和降解系数,讨论了超重糖尿病患者中所发现的变化可能是由于多巴胺和去甲肾上腺素合成减少的可能性。提出了关于糖尿病患者儿茶酚胺排泄减少与超重之间可能的因果关系的推测。