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[自主呼吸新生儿呼吸力学研究的特点。2:评估技术、参数分布及诊断有效性]

[Peculiarities of respiratory mechanical studies in spontaneously breathing newborn infants. 2: Evaluation technics, parameter distribution and diagnostic validity].

作者信息

Schmalisch G, Wauer R R

出版信息

Z Erkr Atmungsorgane. 1984;163(2):121-39.

PMID:6506802
Abstract

Manual evaluation techniques are commonly used until now for the evaluation of recordings. They will be replaced by a computer-aided evaluation of the measuring signals which has several advantages, e.g. reduction of manual expense, processing of high quantities of data, application of powerful algorithms for computation. Both methods are discussed shortly. Hitherto a lot of reference values for the breathing mechanics in newborns have been set up but the various parameters show a wide scatter. This reduces the diagnostical value of breathing mechanical investigations and the clinical interpretation of the measuring results is rendered more difficult. Possibilities for the reduction of the scatter of parameters consist in standardizations of the measurement technique, the investigative conditions and the evaluation techniques as well as in the evaluation of a higher number of breaths in order to get characteristical values for the actual clinical state. The judgment of the diagnostical value of breathing mechanical investigations is commonly based on the subjective assessment by the investigator. Until now systematic investigations for the quantification of the diagnostic value (sensitivity, specifity, predictive value, ...) are not known, because the computation needs a high quantity of data from healthy newborns and such with respiratory distress. The number of cases in the different publications is often too small for these computations. The missing standardization makes it for some purposes impossible to combine the results of the different working groups.

摘要

到目前为止,人工评估技术常用于记录评估。它们将被测量信号的计算机辅助评估所取代,这种评估有几个优点,例如减少人工成本、处理大量数据、应用强大的计算算法。两种方法都将简要讨论。迄今为止,已经建立了许多新生儿呼吸力学的参考值,但各种参数的离散度很大。这降低了呼吸力学检查的诊断价值,也使测量结果的临床解释更加困难。减少参数离散度的方法包括测量技术、研究条件和评估技术的标准化,以及评估更多的呼吸次数,以便获得反映实际临床状态的特征值。呼吸力学检查诊断价值的判断通常基于研究者的主观评估。到目前为止,还没有关于诊断价值量化(敏感性、特异性、预测值等)的系统研究,因为计算需要来自健康新生儿和呼吸窘迫新生儿的大量数据。不同出版物中的病例数量往往太少,无法进行这些计算。缺乏标准化使得在某些情况下无法整合不同工作组的结果。

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