Gutkowski P, Migdał M
Zakladu Fizjologii Oddychania, Instytutu Pomnik-CZD w Warszawie.
Pneumonol Alergol Pol. 1997;65(7-8):465-8.
The aim of the study was to assess the clinical usefulness of lung mechanics measurement in newborns with respiratory distress syndrome. Total respiratory system compliance (Crs) by occlusion technique has been measured in 49 pre-term and in 13 fullterm newborns. All measurements were performed during quiet sleep, newborns were shortly disconnected from respirator and breathed through Fleisch "0". During measurements heart rate and saturation were continuously monitored. Airway pressure was measured downstream of pneumotachometer, occlusions were manually performed. Significantly lower mean Crs values were found in newborns treated with IPPV and IMV in comparison with spontaneously breathing extubated newborns and treated by CPAP. Significantly lower Crs values were found in newborns requiring higher oxygen concentrations in comparison with low oxygen dependent. The results show that newborns with respiratory distress syndrome may be clinically well characterised by Crs value.
本研究的目的是评估肺力学测量在新生儿呼吸窘迫综合征中的临床实用性。采用阻断技术对49例早产儿和13例足月儿的总呼吸系统顺应性（Crs）进行了测量。所有测量均在安静睡眠期间进行，新生儿短暂脱离呼吸机，通过Fleisch“0”呼吸。测量过程中持续监测心率和血氧饱和度。气道压力在呼吸流速计下游测量，阻断操作手动进行。与自主呼吸拔管新生儿和持续气道正压通气（CPAP）治疗的新生儿相比，接受间歇正压通气（IPPV）和间歇指令通气（IMV）治疗的新生儿的平均Crs值显著降低。与低氧依赖新生儿相比，需要更高氧浓度的新生儿的Crs值显著降低。结果表明，呼吸窘迫综合征新生儿的Crs值可在临床上很好地对其进行特征描述。
