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兔、猫和猴的脊髓局部血流量

Regional spinal cord blood flow in the rabbit, cat and monkey.

作者信息

Nyström B, Stjernschantz J, Smedegård G

出版信息

Acta Neurol Scand. 1984 Oct;70(4):307-13. doi: 10.1111/j.1600-0404.1984.tb00828.x.

DOI:10.1111/j.1600-0404.1984.tb00828.x
PMID:6507040
Abstract

Regional blood flow in the spinal cord was measured in rabbits, cats and monkeys with radioactively labelled microspheres. The reproducibility of the method was tested in rabbits by 3 consecutive determinations with differently labelled microspheres within the different cord regions, and was found to be good. In all 3 species, the blood flow was higher in the lumbar part of the cord than in the thoracic part, and in rabbits and monkeys it was also higher in the cervical than in the thoracic part. The flow values for the cervical, lower thoracic and lumbar parts of the cord in rabbits were 33.3, 24.7, and 27.3 ml X min-1 X 100 g-1, respectively, and in monkeys the respective figures were 14.9, 10.5 and 19.7 ml X min-1 X 100 g-1. Corresponding values for cats were only obtained during moderate hyperventilation, and were 12.2, 10.6, and 15.4 ml X min-1 X 100 g-1, respectively. The results are in good accordance with those of previous studies of the blood flow in the spinal cord in which other techniques have been employed.

摘要

采用放射性标记微球对兔、猫和猴的脊髓局部血流进行了测量。通过在兔的不同脊髓区域用不同标记的微球连续进行3次测定,对该方法的可重复性进行了测试,结果发现重复性良好。在所有这3个物种中,脊髓腰段的血流高于胸段,在兔和猴中,颈段的血流也高于胸段。兔脊髓颈段、胸下段和腰段的血流值分别为33.3、24.7和27.3 ml·min⁻¹·100 g⁻¹,猴的相应数值分别为14.9、10.5和19.7 ml·min⁻¹·100 g⁻¹。猫的相应数值仅在中度过度通气时获得,分别为12.2、10.6和15.4 ml·min⁻¹·100 g⁻¹。这些结果与以往采用其他技术对脊髓血流进行研究的结果高度一致。

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