家兔睡眠-清醒周期中脊髓局部血流量的变化

Regional spinal cord blood flow during sleep-waking cycle in rabbit.

作者信息

Lenzi P, Cianci T, Guidalotti P L, Franzini C

出版信息

Am J Physiol. 1986 Nov;251(5 Pt 2):H957-60. doi: 10.1152/ajpheart.1986.251.5.H957.

DOI:10.1152/ajpheart.1986.251.5.H957

Abstract

Spinal cord blood flow (SCBF) was measured in rabbits during the sleep-waking cycle with the use of radioactive microspheres. The values obtained during wakefulness (W), synchronized sleep (SS), and desynchronized sleep (DS) were 18.1 +/- 2.1, 18.9 +/- 2.6, and 34.4 +/- 2.5 (SE) ml X min-1 X 100 g-1, respectively. Differences relative to SS were not significant in W and were significant at the 0.05 level in DS (modified t test and Bonferroni's method). The increase in blood flow during DS was due to a decrease in vascular resistance. The mechanism of the vasodilation during DS has yet to be identified.

摘要

采用放射性微球技术在兔睡眠-觉醒周期中测量脊髓血流量（SCBF）。清醒（W）、同步睡眠（SS）和去同步睡眠（DS）期间测得的值分别为18.1±2.1、18.9±2.6和34.4±2.5（标准误）ml·min⁻¹·100g⁻¹。与SS相比，W期间差异不显著，DS期间差异在0.05水平显著（修正t检验和Bonferroni法）。DS期间血流量增加是由于血管阻力降低。DS期间血管舒张的机制尚待确定。