Bellina J H, Meandzija M P, Schillt V, Voros J I, Berger M, Fick A C, Jackson J D, McNaughton S
Am J Obstet Gynecol. 1984 Dec 15;150(8):934-40. doi: 10.1016/0002-9378(84)90385-5.
In this study we sought to compare laser tissue interaction in both the quasi-continuous waveform and electronically pulsed waveform of the carbon dioxide laser. An intramode analysis of the electronically pulsed form (at 350 and 650 pulses per second) was also undertaken. Intraperitoneal laser incisions were made on New Zealand white female virginal rabbits and tested at days 0, 5, 15, and 20. Testing involved proximal and midsection analysis of the laser sites to evaluate total area of vaporization, total area of tissue thermal damage, maximum diameter of injury at epithelial surface, maximum depth of laser penetration, angle of vaporization crater edges, and angle of tissue thermal injury of the three modes. Analysis of proximal versus midsection preparation revealed different zones of vaporization and injury within the same laser site. The zone of injury with respect to time was nonuniform, suggesting that the laser output in the electronically pulsed mode was not constant. An in vivo tissue lens phenomenon was also detected, resulting in a compound thermal vaporization and injury pattern.
在本研究中，我们试图比较二氧化碳激光在准连续波形和电子脉冲波形下的激光组织相互作用。我们还对电子脉冲形式（每秒350和650个脉冲）进行了模式内分析。在新西兰白色雌性处女兔身上进行腹腔激光切口，并在第0、5、15和20天进行测试。测试包括对激光部位的近端和中间部分进行分析，以评估三种模式下的汽化总面积、组织热损伤总面积、上皮表面损伤的最大直径、激光穿透的最大深度、汽化坑边缘的角度以及组织热损伤的角度。近端与中间部分制备的分析显示，在同一激光部位内存在不同的汽化和损伤区域。损伤区域随时间并不均匀，这表明电子脉冲模式下的激光输出并不恒定。还检测到了一种体内组织透镜现象，导致了复合热汽化和损伤模式。
