Zubenko G S, Cohen B M, Lipinski J F, Jonas J M
Am J Psychiatry. 1984 Dec;141(12):1617-8. doi: 10.1176/ajp.141.12.1617.
The symptoms of three bipolar patients remitted after clonidine treatment. One patient presented with mixed bipolar disorder, two were manic, and all were psychotic. One patient's akathisia also appeared to respond to clonidine. Clonidine's thymoleptic effect paralleled resulting cardiovascular changes.
三名双相情感障碍患者在可乐定治疗后症状缓解。一名患者表现为混合性双相情感障碍,两名患者为躁狂发作,且所有患者均有精神病性症状。一名患者的静坐不能似乎也对可乐定有反应。可乐定的心境稳定作用与随之出现的心血管变化平行。