Melman E P, Shutka B V
Anat Anz. 1984;157(3):199-211.
3 types of mesangiocyte processes have been distinguished in the mesangium of a rat kidney by means of electron-microscopic investigation. Processes of type I contact with proliferations of glomerular capillary endothelium, those of type II begin prolabbing to the capillary, and processes of type III penetrate its lumen. In extreme conditions (simulating in rats of acute ischemia of the kidney with recirculation, compensatory hypertrophy of the remaining kidney) increase of the number and hypertrophy of mesangiocapillary processes of type is observed. Cases of complete displacement of a whole mesangial cell into the capillary have been described. The problem of functional significance of mesangio-capillary processes is being discussed.
通过电子显微镜研究,在大鼠肾脏的系膜中已区分出3种系膜细胞突起。I型突起与肾小球毛细血管内皮细胞的增殖相接触,II型突起开始向毛细血管内突出,III型突起则穿透其管腔。在极端条件下(模拟大鼠急性肾缺血再灌注、残余肾代偿性肥大),可观察到I型系膜毛细血管突起数量增加和肥大。已有描述整个系膜细胞完全移入毛细血管的情况。正在讨论系膜毛细血管突起的功能意义问题。