[低出生体重、小于胎龄新生儿的血脂谱]

[Lipid profile in low birth weight neonates, small for gestational age].

作者信息

Pita M, Sánchez-Pozo A, Gil A, Robles R, Faus M J, Sánchez-Medina F

出版信息

An Esp Pediatr. 1984 Sep 15;21(3):215-21.

Abstract

Serum triglycerides, cholesterol, lipoproteins and fatty acids has been determined in 11 normal infants (RN) and 20 small for date newborn infants (SFD) at birth, before feeding, and at one week of life. All infants were bed with a milk formula (Maseda adaptado ) according with ESPGAN recommendations. Serum triglycerides are significantly increased in SFD after one week of feeding (p less than 0.01). Serum cholesterol in SFD show no differences in relation to normal infants. VLDL are significantly increased in SFD ab birth (p less than 0.01) reaching normal values after one week of feeding. After delivery SFD infants show a low serum level of linoleate (C18:2 omega 6) (p less than 0.05), linolenate (C18:3 omega 3) (p less than 0.02) and eicosadienoate (C20:2 omega 6) (p less than 0.02). No differences are observed in arachidonate (C20:4 omega 6). At one week after feeding no differences are observed in serum fatty acids between SFD and normal infants.

摘要

已对11名正常婴儿（RN）和20名小于胎龄新生儿（SFD）在出生时、喂食前及出生后一周测定了血清甘油三酯、胆固醇、脂蛋白和脂肪酸。所有婴儿均按照欧洲儿科胃肠病学、肝病学和营养学会（ESPGAN）的建议，用一种配方奶（Maseda adaptado）喂养。喂食一周后，SFD组婴儿的血清甘油三酯显著升高（p<0.01）。SFD组婴儿的血清胆固醇与正常婴儿相比无差异。SFD组婴儿出生时极低密度脂蛋白（VLDL）显著升高（p<0.01），喂食一周后达到正常水平。分娩后，SFD组婴儿的血清亚油酸（C18:2ω6）水平较低（p<0.05），亚麻酸（C18:3ω3）水平较低（p<0.02），二十碳二烯酸（C20:2ω6）水平较低（p<0.02）。花生四烯酸（C20:4ω6）未观察到差异。喂食一周后，SFD组婴儿与正常婴儿的血清脂肪酸无差异。