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[系统性栓塞所揭示的创伤性左心室动脉瘤。铟标记血小板的价值]

[Traumatic left ventricular aneurysm disclosed by systemic emboli. Value of platelet labelling with indium].

作者信息

Vahanian A, Villemant D, Grimberg F, Drouet L, Farah E, Acar J

出版信息

Ann Med Interne (Paris). 1984;135(6):452-5.

PMID:6508050
Abstract

The authors report a case of traumatic left ventricular aneurysm, presenting with recurrent cerebral embolism, 36 years after a thoraco-brachial bullet wound. The 58 year old man had no symptoms of angina or particular cardiovascular risk factors. The ECG showed changes of chronic anterior wall infarction, observed 10 years previously on a routine preoperative recording. There was a calcified circular para-apical shadow on chest X-Ray. The antero-apical region showed hypofixation on myocardial scintigraphy, and hypokinesia on isotopic angiography. The coronary arteries were normal. Indium III platelet marking revealed a focus of hyperfixation within the left ventricle. At surgery, a true calcific para-apical left ventricular aneurysm was discovered, containing a fresh thrombus. This lesion was resected. Peroperative Indium III platelet test confirmed that the thrombus was the site of high uptake. The surgical result was good at 6 months follow-up. This case illustrates: the value of the Indium test which would appear to be a very specific and sensitive method of detecting intraventricular thrombi. This test, which appreciates the thrombotic activity of intracardiac masses is a useful complement to other non-invasive methods such as 2D echocardiography; the special characteristics of post-trauma left ventricular aneurysms which are rare, often diagnosed late, at the time of complications such as systemic embolism, commonly pose medico-legal problems, and for which surgical treatment seems to be indicated in symptomatic patients.

摘要

作者报告了一例创伤性左心室动脉瘤病例,该患者在胸臂部枪伤36年后出现反复脑栓塞。这位58岁男性没有心绞痛症状或特殊的心血管危险因素。心电图显示有慢性前壁梗死改变,这是10年前术前常规记录时发现的。胸部X光片显示有一个钙化的圆形心尖旁阴影。心肌闪烁扫描显示心尖前部区域固定不佳,同位素血管造影显示运动减弱。冠状动脉正常。铟III血小板标记显示左心室内有一个高固定灶。手术中发现一个真正的钙化性心尖旁左心室动脉瘤,内有新鲜血栓。切除了该病变。术中铟III血小板检测证实血栓是高摄取部位。术后6个月随访手术效果良好。该病例说明:铟试验的价值,它似乎是检测心室内血栓的一种非常特异和敏感的方法。该试验可评估心内肿块的血栓形成活性,是对二维超声心动图等其他非侵入性方法的有益补充;创伤后左心室动脉瘤的特殊特征,此类动脉瘤罕见,常诊断较晚,在出现全身栓塞等并发症时才被诊断,通常会引发法律问题,对于有症状的患者似乎需要进行手术治疗。

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