Gorozhankina I S, Lishnevskaia E B
Antibiotiki. 1984 Oct;29(10):751-5.
Levorene, a polyenic antibiotic, lowered the concentration of amino acids in the cells of Ehrlich carcinoma. The decrease in the intracellular level of the amino acids was due not only to inhibition of their entrance to the cells but also to their increased leaching from the cells. The effect of levorene on the intracellular level of the neutral amino acids was higher than that on the main amino acids which was associated with different sensitivity of the amino acid transport systems to the antibiotic.
左旋壬烯，一种多烯抗生素，降低了艾氏癌细胞中的氨基酸浓度。细胞内氨基酸水平的降低不仅是由于其进入细胞受到抑制，还由于其从细胞中的渗出增加。左旋壬烯对中性氨基酸细胞内水平的影响高于对主要氨基酸的影响，这与氨基酸转运系统对抗生素的不同敏感性有关。
