Gorozhankina I S, Lishnevskaia E B
Eksp Onkol. 1984;6(4):33-5.
The polyene antibiotic levorin had no effect on the incorporation of 14C-uracil into the pool of intracellular free nucleotides in Ehrlich ascites tumour cells. RNA synthesis was inhibited by the antibiotic only at the late stages of incubation, evidently, due to earlier disturbances of the protein synthesis and in cell energetics.
多烯抗生素左菌素对将14C-尿嘧啶掺入艾氏腹水瘤细胞内游离核苷酸池没有影响。该抗生素仅在培养后期抑制RNA合成,显然,这是由于蛋白质合成和细胞能量代谢较早受到干扰所致。