Mengs U, Schmidt K F, Wolff H G, Goldschmidt R, Tüllner H U
Arch Int Pharmacodyn Ther. 1984 Oct;271(2):315-23.
The objective of the study was to investigate the effects of gangliosides on the regeneration of the sciatic nerve after a crush injury in the rat. After a temporary complete interruption of axonal conduction, nerve conduction velocity was again measurable on the 13th day. On that day and at all subsequent measuring times, the conduction velocity of the damaged nerves was greater in the ganglioside-treated rats than in the control animals which were treated only with the solvent and reached significant values on day 15 and 18.
本研究的目的是探讨神经节苷脂对大鼠坐骨神经挤压伤后再生的影响。在轴突传导暂时完全中断后，第13天再次可测量神经传导速度。在该日及随后所有测量时间，神经节苷脂治疗组大鼠受损神经的传导速度均高于仅用溶剂治疗的对照组动物，并在第15天和第18天达到显著值。
