Poklis A
Drug Alcohol Depend. 1984 Oct;14(2):135-40. doi: 10.1016/0376-8716(84)90039-5.
From 1977 to 1982, the intravenous use of the combination pentazocine/tripelennamine (T's and Blues) had become a major drug abuse problem in St. Louis, MO, U.S.A. In 1983, the manufacturer of pentazocine tablets removed the drug from the pharmaceutical market and released a new tablet formulation of pentazocine and the narcotic antagonist naloxone. Since 1983 there has been a continuous decline in T's and Blues abuse whereby (a) the new pentazocine tablets do not produce the euphoria sought by addicts; (b) the price of old pentazocine tablets has greatly increased and (c) the availability of heroin and other narcotics has increased.
从1977年到1982年，喷他佐辛/曲吡那敏合剂（“T's and Blues”）的静脉注射使用已成为美国密苏里州圣路易斯市一个主要的药物滥用问题。1983年，喷他佐辛片的制造商将该药物撤出药品市场，并推出了喷他佐辛与麻醉拮抗剂纳洛酮的新片剂配方。自1983年以来，“T's and Blues”的滥用情况持续下降，原因如下：（a）新的喷他佐辛片不会产生成瘾者所追求的欣快感；（b）旧喷他佐辛片的价格大幅上涨；（c）海洛因和其他麻醉品的可获得性增加。
