[Effect of the combined use of BCG, PPD, a protein-containing preparation from allogenic tissue and cyclophosphamide in the development of methylcholanthrene-induced tumors].

The organism resistance to the appearance of 20-methylcholanthrene-induced tumours may be enhanced by application of different immunologic factors (BCG, PPD, low-molecular allogenic protein) in combination with a single administration of cyclophosphane (CPh). The positive effect was observed both when CPh was applied prior to the immunologic impact (3 or 7 days before) and after it (3 or 8 days later). In the last case the effect was more stable.