[免疫反应存在时不同品系小鼠对肿瘤发生的抵抗力变化]
[Changes in the resistance of different strains of mice to tumor development in the presence of immunologic responses].
作者信息
Volegov A I
出版信息
Biull Eksp Biol Med. 1978 Nov;86(11):572-4.
PMID:719149
Abstract
The experiments on adult mice of varions breed lines have shown that direction of change of the resistance to cancer under conditions of the same immunological influence can be determined by genetic properties of an organism. The author believes that it is worthy of attention that anticancer resistance decreases only in that lines of mice in which was observed some predisposition to appearing of condition of allergy to tuberculine, as it was shown in experiments using the full adjuvant of Freund.
摘要
对不同品系成年小鼠进行的实验表明，在相同免疫影响条件下，机体对癌症抵抗力的变化方向可由生物体的遗传特性决定。作者认为值得注意的是，只有在对结核菌素出现过敏状态有某种易感性的小鼠品系中，抗癌抵抗力才会下降，这在使用弗氏完全佐剂的实验中得到了证实。
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