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[抗凝系统高活性状态下长春碱对大鼠肉瘤45生长及荷瘤动物多项血液指标的影响]

[Effect of vinblastine during high activity of the anticoagulating system on the growth of sarcoma 45 in rats and several blood indicators in animals with tumors].

作者信息

Kolomina S M, Kalishevskaia T M, Chentsov Iu S, Kudriashov B A, Repina N Iu

出版信息

Eksp Onkol. 1984;6(5):69-72.

PMID:6510348
Abstract

The strong depressive effect of vinblastine on the rat sarcoma 45 growth and intensification of this effect by the combination of vinblastine treatment with the activation of the blood anticoagulating system (BAS) were found. Vinblastine had no negative effect on the BAS activation process and induced no persistent changes in the qualitative content of leucocytes in the peripheral blood.

摘要

发现长春碱对大鼠肉瘤45生长具有强烈的抑制作用，并且通过将长春碱治疗与血液抗凝系统（BAS）激活相结合可增强这种作用。长春碱对BAS激活过程没有负面影响，也不会引起外周血白细胞定性含量的持续变化。

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Eksp Onkol. 1984;6(5):69-72.
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