Fria T J, Doyle W J
Ear Hear. 1984 Nov-Dec;5(6):361-5. doi: 10.1097/00003446-198411000-00008.
A retrospective, cross-sectional analysis of component latencies of the auditory brain stem response (ABR) was performed on 466 patients ranging in age from 30 weeks postconception to adulthood. The ontogeny of ABR component wave latencies was adequately described by two exponential curves having different slopes; the steeper curve represented an early, rapid maturation ending by 8 to 10 weeks post partum, and the ensuing, more gradual curve corresponded to developmental events which were completed by the beginning of the third year of extrauterine life. These observations conform to previous maturational concepts of peripheral versus central segments of the auditory pathway and to the gradual decrease in interwave latencies with increasing age. Unlike interwave latency, however, the ratio of the latencies of selected component waves was constant with increasing age. This was especially apparent in developing newborns less than 50 weeks postconception. The nonlinear bases of this phenomenon are outlined, and the insights which stem from this perspective are discussed.
对466例年龄从孕龄30周直至成年的患者进行了听觉脑干反应（ABR）各成分潜伏期的回顾性横断面分析。ABR成分波潜伏期的个体发育过程可用两条斜率不同的指数曲线充分描述；较陡的曲线代表产后8至10周结束的早期快速成熟，随后较平缓的曲线对应于宫外生活第三年初完成的发育事件。这些观察结果符合听觉通路外周与中枢段先前的成熟概念，以及随着年龄增长波间潜伏期逐渐缩短的情况。然而，与波间潜伏期不同的是，所选成分波潜伏期的比值随年龄增长保持恒定。这在孕龄小于50周的发育中的新生儿中尤为明显。概述了这一现象的非线性基础，并讨论了由此观点得出的见解。
