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健康老年受试者对铁的摄取与排泄

Uptake and excretion of iron by healthy elderly subjects.

作者信息

Bunker V W, Lawson M S, Clayton B E

出版信息

J Clin Pathol. 1984 Dec;37(12):1353-7. doi: 10.1136/jcp.37.12.1353.

Abstract

Metabolic balance studies for iron have been carried out on 24 apparently healthy elderly people (11 men and 13 women) aged 69.7 to 85.5 years living in their own homes and eating self selected diets. Several biochemical and haematological indices of iron state were also measured. The mean daily iron intake was 176 mumol, with a range of 55-321 mumol. Eight women and six men consumed diets which provided less than the recommended daily dietary allowance for iron of 179 mumol/day. Mean daily retention of iron, however, was -7 mumol, a value which did not significantly differ from equilibrium. No sex difference was noted between any of the biochemical and haematological measurements. Mean values of iron concentration, iron binding capacity, iron binding saturation, and ferritin and haemoglobin concentrations were 20 mumol/l, 59 mumol/l, 34%, 77 micrograms/l, and 14.3 g/dl, respectively. We have shown that in apparently healthy elderly people who are in equilibrium for iron balance, several biochemical and haematological measurements of iron state do not differ from the normal ranges established in younger adults.

摘要

对24名年龄在69.7至85.5岁、居家生活且饮食自主选择的健康老年人(11名男性和13名女性)进行了铁代谢平衡研究。还测量了铁状态的多项生化和血液学指标。每日铁摄入量平均为176微摩尔,范围为55 - 321微摩尔。8名女性和6名男性的饮食中铁摄入量低于推荐的每日膳食摄入量179微摩尔/天。然而,铁的平均每日潴留量为 - 7微摩尔,该值与平衡状态无显著差异。在任何生化和血液学测量中均未发现性别差异。铁浓度、铁结合能力、铁结合饱和度、铁蛋白和血红蛋白浓度的平均值分别为20微摩尔/升、59微摩尔/升、34%、77微克/升和14.3克/分升。我们已经表明,在铁平衡处于平衡状态的明显健康的老年人中,铁状态的多项生化和血液学测量结果与年轻人确定的正常范围没有差异。

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