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对明显健康的荷兰自由生活老年人群体的维生素和铁状况进行生化评估。与年轻人进行比较。

Biochemical evaluation of the vitamin and iron status of an apparently healthy Dutch free-living elderly population. Comparison with younger adults.

作者信息

Schrijver J, van Veelen B W, Schreurs W H

出版信息

Int J Vitam Nutr Res. 1985;55(3):337-49.

PMID:4077406
Abstract

In order to obtain information on "normal" values, the vitamin and iron status have been investigated of an apparently healthy Dutch elderly population, living in their own homes in the centre of the Netherlands. In total 99 women and 99 men (overall mean age 72 yrs) volunteered in the study. By omitting the elderly suffering from one or more diseases as well as those using vitamin supplements, 131 aged people were selected for the biochemical evaluation of the vitamin and iron status of healthy elderly. Results have been compared with those obtained for healthy adults below 50 years of age. The "normal" values obtained appear to deviate significantly from those of the group of apparently healthy younger adults for several vitamins. Especially, lower values were observed for the vitamin A, total carotenoids, vitamin D, B6, B12 and folic acid status. Furthermore, lower serum iron and iron saturation as well as creatinine excretion with the urine were found as compared to healthy younger adults. Apparently, only in the case of vitamin B6, there is serious doubt about the adequacy of the status of the elderly, which needs further investigation. As far as has been investigated, it appeared that reference values derived from a population of apparently healthy adults below 50 years of age are not applicable to apparently healthy elderly.

摘要

为了获取“正常”值的相关信息,对居住在荷兰中部自己家中、看似健康的荷兰老年人群体的维生素和铁状况进行了调查。共有99名女性和99名男性(总体平均年龄72岁)自愿参与了该研究。通过排除患有一种或多种疾病的老年人以及正在使用维生素补充剂的老年人,挑选出131名老年人对健康老年人的维生素和铁状况进行生化评估。研究结果已与50岁以下健康成年人的研究结果进行了比较。所获得的“正常”值在几种维生素方面似乎与看似健康的年轻成年人组的数值有显著差异。特别是,维生素A、总类胡萝卜素、维生素D、B6、B12和叶酸状况的数值较低。此外,与年轻健康成年人相比,血清铁和铁饱和度以及尿肌酐排泄量也较低。显然,仅就维生素B6而言,老年人状况是否充足存在严重疑问,这需要进一步调查。就目前所调查的情况来看,从50岁以下看似健康的成年人人群得出的参考值并不适用于看似健康的老年人。

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