O'Shaughnessy R W, Hackett K J
J Reprod Med. 1984 Oct;29(10):752-6.
Maternal Addison's disease (primary hypoadrenalism) is an infrequent complication of pregnancy that poses a high risk of maternal mortality if not recognized and treated. If adequate steroid replacement therapy is provided, however, there is little risk for the mother during pregnancy. We treated a woman for previously undiagnosed Addison's disease during pregnancy that apparently interfered with normal fetal growth. This case supports Osler's observation that maternal Addison's disease can cause intrauterine fetal growth retardation.
妊娠合并艾迪生病(原发性肾上腺皮质功能减退症)是一种罕见的妊娠并发症,如果未被识别和治疗,会导致很高的孕产妇死亡风险。然而,如果给予足够的类固醇替代疗法,孕期母亲的风险很小。我们治疗了一名在孕期患有先前未确诊的艾迪生病的女性,该病显然干扰了胎儿的正常生长。该病例支持奥斯勒的观察结果,即妊娠合并艾迪生病可导致胎儿宫内生长受限。