Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Int J Environ Res Public Health. 2019 Mar 4;16(5):781. doi: 10.3390/ijerph16050781.
Pregnancy in women with associated endocrine conditions is a therapeutic challenge for clinicians. These disorders may be common, such us thyroid disorders and diabetes, or rare, including adrenal and parathyroid disease and pituitary dysfunction. With the development of assisted reproductive techniques, the number of pregnancies with these conditions has increased. It is necessary to recognize symptoms and correct diagnosis for a proper pharmacotherapeutic management in order to avoid adverse side effects both in mother and fetus. This review summarizes the pharmacotherapy of these clinical situations in order to reduce maternal and fetal morbidity.
患有相关内分泌疾病的女性妊娠对临床医生来说是一个治疗挑战。这些疾病可能很常见,如甲状腺疾病和糖尿病,也可能很罕见,包括肾上腺和甲状旁腺疾病以及垂体功能障碍。随着辅助生殖技术的发展,这些疾病的妊娠数量有所增加。为了避免母亲和胎儿出现不良反应,有必要识别症状并做出正确诊断,以便进行适当的药物治疗管理。本文综述了这些临床情况的药物治疗,以降低母婴发病率。