Harris J R, Finger R F, Kobayashi J M, Hadler S C, Murphy B L, Berkelman R L, Bussell K E
JAMA. 1984 Dec 21;252(23):3270-2.
To determine the risk of hepatitis B virus infection for rural hospital employees, we obtained serum and a completed questionnaire from each of 2,064 employees of 11 rural hospitals. Only 96 (4.7%) employees had hepatitis B virus markers. Increased marker prevalence was significantly associated with prior residence in a city with a population of greater than 100,000 (odds ratio, 2.9; 95% confidence interval, 1.6 to 5.2) and increasing blood contact (odds ratio, 1.6; confidence interval, 1.2 to 2.3); however, the association with blood contact was not significant when we limited analysis to the 836 employees who had never lived in a city. We conclude that the risk of hepatitis B virus infection for these rural hospital employees is low, probably because the incidence of hepatitis B in rural areas is low.
为确定农村医院员工感染乙型肝炎病毒的风险，我们从11家农村医院的2064名员工中每人获取了血清样本并填写了完整问卷。仅有96名（4.7%）员工有乙型肝炎病毒标志物。标志物患病率增加与之前居住在人口超过10万的城市显著相关（比值比为2.9；95%置信区间为1.6至5.2），且与血液接触增加相关（比值比为1.6；置信区间为1.2至2.3）；然而，当我们将分析局限于836名从未在城市生活过的员工时，与血液接触的关联并不显著。我们得出结论，这些农村医院员工感染乙型肝炎病毒的风险较低，可能是因为农村地区乙型肝炎的发病率较低。
