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伤口闭合:收缩与上皮形成的相对贡献分析

Wound closure: an analysis of the relative contributions of contraction and epithelialization.

作者信息

Snowden J M

出版信息

J Surg Res. 1984 Dec;37(6):453-63. doi: 10.1016/0022-4804(84)90213-0.

DOI:10.1016/0022-4804(84)90213-0
PMID:6513541
Abstract

The behavior of excisional wounds in rat and man has been analyzed. The rate of change in wound area due to contraction has been shown to be consistent with a constant linear rate of movement of the wound margins. The rate of change of area due to epithelialization has been shown to be consistent with a constant linear rate of growth of the epithelium. These rates together with the relevant delay times are shown to be the appropriate parameters for the comparison of the behaviors of excisional wounds. These parameters can be calculated from the change in wound area with time. An unexpected finding was that in both rat and man, the values obtained for the rates of contraction and epithelialization varied widely but the combined rates of these two processes varied little.

摘要

已对大鼠和人类切除伤口的行为进行了分析。结果表明,由于伤口收缩导致的伤口面积变化率与伤口边缘恒定的线性移动速率一致。由于上皮化导致的面积变化率已被证明与上皮恒定的线性生长速率一致。这些速率以及相关的延迟时间被证明是比较切除伤口行为的合适参数。这些参数可以根据伤口面积随时间的变化来计算。一个意外的发现是,在大鼠和人类中,收缩率和上皮化率的值差异很大,但这两个过程的综合速率变化很小。

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