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烧伤创面愈合与治疗:综述与进展

Burn wound healing and treatment: review and advancements.

作者信息

Rowan Matthew P, Cancio Leopoldo C, Elster Eric A, Burmeister David M, Rose Lloyd F, Natesan Shanmugasundaram, Chan Rodney K, Christy Robert J, Chung Kevin K

机构信息

United States Army Institute for Surgical Research, 3698 Chambers Pass, Fort Sam Houston, TX, 78234, USA.

Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.

出版信息

Crit Care. 2015 Jun 12;19:243. doi: 10.1186/s13054-015-0961-2.

DOI:10.1186/s13054-015-0961-2
PMID:26067660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4464872/
Abstract

Burns are a prevalent and burdensome critical care problem. The priorities of specialized facilities focus on stabilizing the patient, preventing infection, and optimizing functional recovery. Research on burns has generated sustained interest over the past few decades, and several important advancements have resulted in more effective patient stabilization and decreased mortality, especially among young patients and those with burns of intermediate extent. However, for the intensivist, challenges often exist that complicate patient support and stabilization. Furthermore, burn wounds are complex and can present unique difficulties that require late intervention or life-long rehabilitation. In addition to improvements in patient stabilization and care, research in burn wound care has yielded advancements that will continue to improve functional recovery. This article reviews recent advancements in the care of burn patients with a focus on the pathophysiology and treatment of burn wounds.

摘要

烧伤是一个普遍且棘手的重症监护问题。专业机构的工作重点在于稳定患者病情、预防感染以及优化功能恢复。在过去几十年里,对烧伤的研究一直备受关注,多项重要进展使得患者病情稳定更加有效,死亡率降低,尤其是在年轻患者和中度烧伤患者中。然而,对于重症监护医生来说,常常存在一些挑战,使患者的支持和稳定工作变得复杂。此外,烧伤创面复杂,可能带来一些独特的难题,需要后期干预或终身康复治疗。除了在患者病情稳定和护理方面取得的进展外,烧伤创面护理研究也取得了进步,这将继续改善功能恢复情况。本文综述了烧伤患者护理的最新进展,重点关注烧伤创面的病理生理学和治疗。

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本文引用的文献

1
Nutrition and anabolic pharmacotherapies in the care of burn patients.烧伤患者护理中的营养与合成代谢药物治疗
Nutr Clin Pract. 2014 Oct;29(5):621-30. doi: 10.1177/0884533614533129.
2
Do silver-based wound dressings reduce pain? A prospective study and review of the literature.银基伤口敷料能减轻疼痛吗?一项前瞻性研究及文献综述。
Burns. 2014 Dec;40 Suppl 1:S40-7. doi: 10.1016/j.burns.2014.09.012.
3
Low dose of glucocorticoid decreases the incidence of complications in severely burned patients by attenuating systemic inflammation.低剂量糖皮质激素通过减轻全身炎症反应降低重度烧伤患者并发症的发生率。
J Crit Care. 2015 Apr;30(2):436.e7-11. doi: 10.1016/j.jcrc.2014.09.016. Epub 2014 Sep 22.
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Wound healing trajectories in burn patients and their impact on mortality.烧伤患者的伤口愈合轨迹及其对死亡率的影响。
J Burn Care Res. 2014 Nov-Dec;35(6):474-9. doi: 10.1097/BCR.0000000000000039.
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Review of burn research for the year 2013.2013年烧伤研究综述。
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6
On the horizon: research priorities in burns for the next decade.展望未来:未来十年烧伤研究重点。
Surg Clin North Am. 2014 Aug;94(4):917-30. doi: 10.1016/j.suc.2014.05.012. Epub 2014 Jun 16.
7
Epithelialization in Wound Healing: A Comprehensive Review.伤口愈合中的上皮化:综述
Adv Wound Care (New Rochelle). 2014 Jul 1;3(7):445-464. doi: 10.1089/wound.2013.0473.
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