Dabrowski Z, Wójcicki J
Methods Find Exp Clin Pharmacol. 1984 Sep;6(9):509-11.
The authors performed a chronic pancreatic fistula in the dog by a modified method of Herrera et al. in which one of the arms of a metal cannula is introduced into the stomach instead of the duodenum. This technique protects the duodenum, the main source of hormones acting on the pancreas in the digestive tract, from surgical trauma and its consequences. The duodenum is anastomosed end-to-end and the continuity of the digestive tract is restored. The model can next be used to study the action of drugs on the exocrine function of the pancreas.
作者采用对埃雷拉等人方法的改良，在犬身上制造慢性胰瘘，即将金属套管的一个分支插入胃而非十二指肠。该技术可保护十二指肠（消化道中作用于胰腺的激素的主要来源）免受手术创伤及其后果的影响。十二指肠进行端端吻合，恢复消化道的连续性。接下来，该模型可用于研究药物对胰腺外分泌功能的作用。
